Biological data comes in many forms. For the past 20 years, much of the attention has focussed on genomics because on the the fundamental role that genes play in disease. Today genetic tests are commonly used as a diagnostic; but these tests remain relatively expensive and inconvenient.
In parallel other 'omic disciplines such as proteomics, metabolomics and epigenomics have provided context to genomic information - often providing additional clinical insights which have added to our ability to diagnose and manage disease.
Imageomics provides yet further context to the expanding 'omics field: While the structures seen in medical images are obviously at a far larger scale, they ultimately reflect underlying genomic, proteomic, metabolic and epigenetic processes.
In ophthalmology for example, it is possible to measure the distance between any of the 15 layers of the retina, from images like those above. Abnormal measurements might be signs of an underlying disease, which can often become apparent years before the disease becomes clinically evident. Early signs of renal, brain and cardiovascular disease have all been found in images like these.
What's more, these traits can be detected cheaply and conveniently using equipment found in doctors offices or, in this example, a high street opticians.
But extracting information from images is very resource intensive. Therefore a central part of imageomics is the ability to use artificial intelligence to automate the analysis of images at scale. This is technically complex and computationally demanding, requiring very high quality and carefully curated real-world data, such as that found within RAIR's broader Oculair™ solution.
Nonetheless, when used in combination with other 'omics technologies, imageomics promises to help build a more complete picture of health and provide a convenient way of diagnosing patients earlier. In due course, imageomics may also identify novel biomarkers of disease which might be used to better manage patients or even serve as drug targets in their own right.
RAIR's Imageomics Workflow
RAIR Health has built a clinical image processing workflow which, together with algorithms written for Oculair™, can assist researchers in image-based clinical fields to spot hidden patterns and associations between a range of 'omic datasets, which might have valuable clinical applications.
What can RAIR do for you? Please check out our website or fact sheet or get in touch with us today so that we can set up a demo.
RAIR Health Limited
Health Foundry, Canterbury House, 1 Royal St, London, SE1 7LL
Copyright © 2021 RAIR Health Limited - All Rights Reserved.
What are cookies and how do they work?
“Cookies” are text-only pieces of information that a website transfers to an individual’s hard drive or other website-browsing equipment for record-keeping purposes. Cookies allow the website to remember important information that will make your use of the site more convenient. A cookie will typically contain the name of the domain from which the cookie has come, the “lifetime” of the cookie, and a randomly generated unique number or other value. Like most websites, we use different categories of cookies for a variety of purposes in order to improve your online experience.
Depending on the purpose, we use session cookies, which are temporary cookies that remain in the cookie file of your browser until you leave the site, and persistent cookies, which remain in the cookie file of your browser for 20 years.
What are the categories of cookies?
Cookies can be categorised, following the International Chamber of Commerce guide, as follows:
Strictly necessary cookies
‘Strictly necessary cookies’ tend to be session cookies which are deleted at the end of the browser session.
Accepting these cookies is a condition of using the website, so if you prevent these cookies, we can’t guarantee how our website will perform during your visit.
‘Performance cookies’ collect information about how you use our website such as which pages you visit and if you experience any errors. These cookies don’t collect any information that could identify you – all the information is collected on an anonymous aggregate basis and is only used to help us improve how our website works, understand what interests our users and measure the effectiveness of our advertising. They also enable us to track the total number of visitors to our site. Most performance cookies tend to be session cookies which are deleted at the end of the browser session.
In some cases, some of these cookies are managed for us by third parties, but we don’t allow the third party to use the cookies for any purpose other than those listed above. Some of these third-party performance cookies are persistent cookies.
Functionality cookies, by their very nature, are persistent cookies so that we remember your computer when you return to our website.
Some of these cookies are managed for us by third parties – where this is the case, we don’t allow the third party to use the cookies for any purpose other than those listed above.
How can I block and/or delete cookies?
Use the options in your web browser if you do not wish to receive a cookie or if you wish to set your browser to notify you when you receive a cookie. You can easily delete any cookies that have been installed in the cookie folder of your browser.